If there were ever a Benjamin Button in real life, it would be Demi Moore. The only explanation for the phenomenon of her becoming so noticably hotter by the day is some kind of voodoo black magic. Watch out, Ashton – she's stealing your youth!
Clooney was a goofy mulleted carpenter when he first guest-starred on "The Facts of Life." Though first impressions didn't seem to matter so much when he accepted People Magazine's title of "Sexiest Man Alive" twenty years later.
Kate Winslet probably looks even better naked today than she did ten years ago in "Titanic". Just hurry up and give her the Oscar she deserves so she can stop trying to win awards and start doing… I don't know… erotic thrillers?
Decades before his McDreamy days on "Grey's," Patrick Dempsey was a nerd who had to pay for dates in "Can't Buy Me Love". In "Loverboy" he was a pizza boy who charmed the pants off of older ladies – a skill he continues to employ, without anchovies.
Thanks to yoga, cardio, The Zone Diet and a hefty bank account, Ben Button's ex-wife has the bod at 40 that she dreamed of at 20 — and a hot boyfriend 9 years her junior. So lay off, Us Weekly: Jen looks too dang hot to care about Brangelina.
Back in the '90s, Affleck was just a regular schlub with a grubby goatee. But once he lost the face fuzz, Ben won an Oscar, married Jen Garner, and became a critically-acclaimed director. Scummy "Dazed and Confused" bully O'Bannion is all grown up.
Sarah Palin may have been a beauty pageant contestant, but Tina Fey was the swan of SNL portraying the would-be VP last fall. No offense to funny ladies, but there aren't many who've made Maxim's Hot 100 list. How does this baby mama do it?
Captain Johnny Depp is mid-forties, yet remains "forever 21 Jump Street", the heartthrob of choice for generations of mothers, daughters, sisters, brothers and people who haven't even been born yet.
Marisa Tomei's biological clock may in fact be at a standstill. Case in point: seventeen years after her first Oscar win for "My Cousin Vinny", hottie-tottie Tomei has been nominated for another Academy Award… for her role as a stripper.